Antiphospholipid syndrome. Specificity of antiphospholipid antibodies and thrombosis.

Prevalence of Antiphospholipid Antibodies in Syrian Patients with Thrombosis

Background: Antiphospholipid antibodies (aPL) are a heterogeneous family of anti-bodies associated with thrombosis and other complications. Objective: To study the prevalence of aPL in patients with thrombosis at Aleppo University Hospitals, Syria. Methods: One hundred and fifty-seven patients with venous and arterial thrombosis and 63 healthy controls were studied. Anticardiolipin antibodies (...

Antiphospholipid Syndrome and Antibodies

Antiphospholipid syndrome is an acquired thrombophilia characterized by venous or artery thrombosis sometimes accompanied by thrombocytopenia in the presence of anti-phospholipid antibodies. The 14th International Antiphos-pholipid Antibodies Congress was combined with the 4th Latin American Congress on Autoimmunity and took place in Rio de Janeiro in September 2013. In this special issue we ha...

Antiphospholipid Syndrome Presenting with Superior Vena Cava Thrombosis

Thrombosis and the antiphospholipid syndrome.

The antiphospholipid syndrome is an antibody-mediated hypercoagulable state characterized by recurrent venous and arterial thromboembolic events. Several studies have determined that the frequency of antiphospholipid syndrome in patients presenting with a venous thromboembolic event is between 4% and 14%. Because of the high risk for recurrent thromboembolism in these patients, current recommen...

Antiphospholipid antibodies and thrombosis: strength of association.

Antiphospholipid antibodies, that is, lupus anticoagulants and anticardiolipin antibodies, are associated with thrombosis and obstetric complications in the antiphospholipid syndrome. Venous thrombosis occurs mostly in the lower limbs, with or without pulmonary embolism, and cerebral ischemia and transient ischemic attacks are the most common arterial events. Overall, the prevalence of thrombos...